New Gel for Men: The Contraception of the Future

After a decade of intense research, American scientists are ready to begin trials for a revolutionary male contraceptive—a gel that blocks sperm production. This innovative product, containing two synthetic hormones, progestin and testosterone, will be part of the largest study of male hormonal contraceptives ever conducted in the U.S.

After a decade of intense research, American scientists are ready to begin trials for a revolutionary male contraceptive—a gel that blocks sperm production. This innovative product, containing two synthetic hormones, progestin and testosterone, will be part of the largest study of male hormonal contraceptives ever conducted in the U.S.

Clinical trials will start in April and last for four years. Over 400 couples from the U.S., the U.K., Italy, Sweden, Chile, and Kenya will participate in this landmark study. This experiment represents a significant step towards creating an effective and convenient contraceptive option for men.

Progestin in the gel blocks the production of testosterone needed for normal sperm levels, while testosterone itself is necessary to maintain hormonal balance. The gel must be applied to the shoulders daily, and its effects last up to 72 hours, making it convenient even if a dose is missed.

During the trials, couples will use the new contraceptive in conjunction with female methods to monitor the reduction in sperm count, which must drop to less than one million per millimeter to minimize pregnancy risk. Once this target is reached, couples will switch exclusively to the gel for a year, discontinuing female contraceptives.

Initially, the contraceptive was tested as two separate gels applied to different body areas. However, after modifying the formula and combining the gels into one product, experts are confident in its effectiveness and ease of use. This new method is superior to pills, as testosterone remains in the bloodstream longer when applied as a gel.

This innovative approach to male contraception could revolutionize family planning and significantly expand contraceptive options for men.